Cellular Landscape: a part of the immune system story

This was my final project for the 3D class I was taking this last semester depicting one part of adaptive immunity.  Here’s a technical description of what is being depicted:

The bacteria (long yellow cells) are traveling through an artery. One of these bacterium gets gobbled up by the naive B cell that happens to have a corresponding receptor protein that binds to that particular antigen (the bacterium).  That B cell breaks down the bacterium internally then displays chunks of the antigen on MHC molecules on the cell’s surface.  A helper T cell (shown in blue) is then needed to complete the activation of the B cell at which point it will differentiate into plasma cells and memory B cells (not depicted).   The plasma cells secrete antibodies (IgM and IgG shown) which attach to the exterior of the antigen that triggered the response (the bacteria), thus marking that antigen for destruction.  To finish off, a macrophage (upper right corner) is shown phagocytosing the tagged bacteria.

This piece was modeled in 3ds Max and composited in Photoshop. It was a lot of fun to work on.

A Cellular Landscape of the Immune Process: one tiny part of the whole story

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: