Cellular Landscape: a part of the immune system story

This was my final project for the 3D class I was taking this last semester depicting one part of adaptive immunity.  Here’s a technical description of what is being depicted:

The bacteria (long yellow cells) are traveling through an artery. One of these bacterium gets gobbled up by the naive B cell that happens to have a corresponding receptor protein that binds to that particular antigen (the bacterium).  That B cell breaks down the bacterium internally then displays chunks of the antigen on MHC molecules on the cell’s surface.  A helper T cell (shown in blue) is then needed to complete the activation of the B cell at which point it will differentiate into plasma cells and memory B cells (not depicted).   The plasma cells secrete antibodies (IgM and IgG shown) which attach to the exterior of the antigen that triggered the response (the bacteria), thus marking that antigen for destruction.  To finish off, a macrophage (upper right corner) is shown phagocytosing the tagged bacteria.

This piece was modeled in 3ds Max and composited in Photoshop. It was a lot of fun to work on.

A Cellular Landscape of the Immune Process: one tiny part of the whole story

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